Publication Details
Abstract
Toxoplasma gondii is a known worldwide occurring, dangerous parasite which has the highest impacts on pregnant women, and results into abortions, fetus deformities etc among others. Likewise Human Cytomegalovirus (CMV), another beta human Herpesvirus type 5 is an example of a virus which has a clinical significance in healthy adults exhibiting lifelong asymptomatic infection while presenting significant morbidity and mortality in Neonates and Immunocompromised clients. Some of the gestational infections that are of great clinical concern include rubella, which although has reduced prevalence because of vaccination. The purpose of this study was to analyze the seroprevalence of Toxoplasmosis, CMV, and Rubella amongst pregnant womens who had miscarriage in Kirkuk city. Also, the study aimed at establishing pathological feature of the placentae and umbilical cords in these infections. The blood samples of pregnant women who had miscarriages were taken between the month of January, 2022 and March, 2022. Demographic data of each participant were obtained using a structured self-administered questionnaire. Five millilitre of blood was withdrawn from each subject; the blood was allowed to coagulate before being centrifuged for further analysis. The Toxoplasmosis and CMV serological tests were tested using latex agglutination with positive and negative controls and IGG/IgM test cassettes. Blood tests involved the method of cell counting through measurement of electrical impedance and light absorbance for size, number and cellular contents of the blood. In the research, the authors discovered an average score of 0. 6% for anti T. gondii IgM antibodies and 15% for anti CMV IgM antibodies in the women of age group 18-49 years. 0%. The overall rate of IgG antibodies was 13. six for R. raccoon, 8% for T. gondii and a mean of 6. 3% for CMV. The study also observed low packed cell volume, reduced concentration of red blood cells, white blood cells, hemoglobin and decreased means of corpuscular volume among the infected individuals particularly among the women with chronic kidney disease caused by T. gondii, CMV and Rubella. The findings of this study show that 32 (80%) out of the women who had miscarriages in Kirkuk city tested positive for CMV, while 18 (45%) tested positive for Toxoplasma gondii With considerable hematological changes concerning these infections. It is, therefore, the need to come up with early detection and intervention measures that may reduce the impact of these infections to pregnancy outcomes. More research is needed in order to come up with extensive prevention and treatment strategies in areas with similar health issues.